Paper Title :Mutation Analysis of Cd117 in Hepatocellular Carcinoma
Author :Nicholas C. Hsu, Chih-Yuan Chung
Article Citation :Nicholas C. Hsu ,Chih-Yuan Chung ,
(2016 ) " Mutation Analysis of Cd117 in Hepatocellular Carcinoma " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 226-228,
Volume-4,Issue-3, Spl. Iss-1
Abstract : The aim of this study was to investigate the presence of activating CD117 gene mutation in hepatocellular
carcinoma (HCC). Twenty-two CD117 positive HCC specimens confirmed by immunohisto chemical staining and RT-PCR
were analyzed. All specimens were screened for mutations in exons 9 and 11 of the CD117 gene by direct sequencing. No
sequence abnormalities were detected. These results suggest that the expression of CD117 tyrosine kinase is independent of
mutation in exons 9 and 11 of HCC.
Keywords- CD117, Hepatocellular Carcinoma, Receptor Tyrosine Kinase.
Type : Research paper
Published : Volume-4,Issue-3, Spl. Iss-1
DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-5336
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Copyright: © Institute of Research and Journals
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Published on 2016-09-12 |
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