Paper Title :Particle Simulation of Skin Formation: Relationship Between Skin Homeostasis and Bound Water

Author :Katsuya Nagayama, Shu Oba

Article Citation :Katsuya Nagayama ,Shu Oba , (2024 ) " Particle Simulation of Skin Formation: Relationship Between Skin Homeostasis and Bound Water " , International Journal of Advances in Science, Engineering and Technology(IJASEAT) , pp. 47-50, Volume-12,Issue-1

Abstract : As the epidermis adapts to different environments, the desquamation of keratinocytes is affected by the water content of the epidermis. The thickness of the stratum corneum is determined by the interaction between exfoliation and water content. The balance between these processes is the key to healthy skin. In this study, a numerical model of stratum corneum thickness was constructed based on the interaction between exfoliation and water content. In this model, free water on the skin surface is removed, and skin homeostasis is expressed by focusing on the differences in the amount of bound water. This numerical simulation presents that when the skin is dry, keratin tends to increase because of the regulation mechanism; however, when the skin is too dry, the accumulated keratin clumps up and easily peels off. Keywords - Particle simulation, Skin, Stratum corneum, Homeostasis, Bound water.

Type : Research paper

Published : Volume-12,Issue-1

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