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Paper Title :
Mutation Analysis of Cd117 in Hepatocellular Carcinoma

Author :Nicholas C. Hsu, Chih-Yuan Chung

Article Citation :Nicholas C. Hsu ,Chih-Yuan Chung , (2016 ) " Mutation Analysis of Cd117 in Hepatocellular Carcinoma " , International Journal of Advances in Science, Engineering and Technology(IJASEAT) , pp. 226-228, Volume-4,Issue-3, Spl. Iss-1

Abstract : The aim of this study was to investigate the presence of activating CD117 gene mutation in hepatocellular carcinoma (HCC). Twenty-two CD117 positive HCC specimens confirmed by immunohisto chemical staining and RT-PCR were analyzed. All specimens were screened for mutations in exons 9 and 11 of the CD117 gene by direct sequencing. No sequence abnormalities were detected. These results suggest that the expression of CD117 tyrosine kinase is independent of mutation in exons 9 and 11 of HCC. Keywords- CD117, Hepatocellular Carcinoma, Receptor Tyrosine Kinase.

Type : Research paper

Published : Volume-4,Issue-3, Spl. Iss-1


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