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Paper Title :
Evaluation of Brucella Antigens in Serological Diagnosis of Brucellosis

Author :Aitbay K.Bulashev, Zhanbolat A.Suranshiev, Aibek.Kh.Zhumalin, Kanat A. Tursunov

Article Citation :Aitbay K.Bulashev ,Zhanbolat A.Suranshiev ,Aibek.Kh.Zhumalin ,Kanat A. Tursunov , (2016 ) " Evaluation of Brucella Antigens in Serological Diagnosis of Brucellosis " , International Journal of Advances in Science, Engineering and Technology(IJASEAT) , pp. 138-140, Volume-4,Issue-3, Spl. Iss-1

Abstract : The diagnostic value of Brucella spp. outer membrane proteins (OMPs) in Enzyme-linked immunosorbent assay (ELISA) for serological diagnosis of cattle brucellosis has been studied. It was established that B. abortus 19 and B. melitensis Rev-1 OMPs possess distinct antigenicity to antibodies of cows with positive results for brucellosis by Serum Agglutination Test and Complement Fixation Test. Brucella OMPs significantly exceeded the recombinant protein with a molecular weight of 26 kDa by their antigenicity. The results suggest that in the development of ELISA-tests for diagnosing brucellosis not single, but combination of several recombinant proteins should be used. Keywords- Antigenicity, Brucella spp., Enzyme-linked immunosorbent assay, Outer membrane proteins.

Type : Research paper

Published : Volume-4,Issue-3, Spl. Iss-1


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