Paper Title :Evaluation of Brucella Antigens in Serological Diagnosis of Brucellosis
Author :Aitbay K.Bulashev, Zhanbolat A.Suranshiev, Aibek.Kh.Zhumalin, Kanat A. Tursunov
Article Citation :Aitbay K.Bulashev ,Zhanbolat A.Suranshiev ,Aibek.Kh.Zhumalin ,Kanat A. Tursunov ,
(2016 ) " Evaluation of Brucella Antigens in Serological Diagnosis of Brucellosis " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 138-140,
Volume-4,Issue-3, Spl. Iss-1
Abstract : The diagnostic value of Brucella spp. outer membrane proteins (OMPs) in Enzyme-linked immunosorbent assay
(ELISA) for serological diagnosis of cattle brucellosis has been studied. It was established that B. abortus 19 and B.
melitensis Rev-1 OMPs possess distinct antigenicity to antibodies of cows with positive results for brucellosis by Serum
Agglutination Test and Complement Fixation Test. Brucella OMPs significantly exceeded the recombinant protein with a
molecular weight of 26 kDa by their antigenicity. The results suggest that in the development of ELISA-tests for diagnosing
brucellosis not single, but combination of several recombinant proteins should be used.
Keywords- Antigenicity, Brucella spp., Enzyme-linked immunosorbent assay, Outer membrane proteins.
Type : Research paper
Published : Volume-4,Issue-3, Spl. Iss-1
Copyright: © Institute of Research and Journals
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Published on 2016-09-12 |
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