International Journal of Advances in Science, Engineering and Technology(IJASEAT)
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Volume-7,Issue-1, Spl. Iss-2  ( Mar, 2019 )
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  Journal Paper

Paper Title
Synthesis and Biological Evaluation of Schiff Base Derivatives of Furfural based Heterocyclic Flavones

Abstract
Synthesized a total of twelve new furfural flavone Schiff base derivatives starting from commercially available phloroglucinol. In the first stage the corresponding acetophenone key intermediate was synthesized from the starting material and was condensed with furfural followed by cyclisation, and formylation. Finally, the formylated flavone was condensed with various aromatic primary amines to obtain the desired Schiff base derivatives. All the synthesized furfural flavone Schiff base derivatives were tested for their anticancer and antibacterial activities and the results were analysed in the light of their structural activity. Index Terms - Furfuralflavone, Aromatic Amines, Schiff Bases, Antibacterial Activity.


Author - Hari Babu Bollikolla, Bala Murali Krishna Khandapu

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