Paper Title :Metronomic Chemotherapy: Changing the Approach that Bigger is always Better
Author :Bhushan Jain, Nikhil Raka
Article Citation :Bhushan Jain ,Nikhil Raka ,
(2017 ) " Metronomic Chemotherapy: Changing the Approach that Bigger is always Better " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 34-35,
Volume-5, Issue-4, Spl. Iss-2
Abstract : Conventional chemotherapy and even new drug delivery systems lead to adverse drug reactions that restrict
dosing and interferes the efficacy of antineoplastic drugs. So exploring new therapeutic targets as well as new therapeutic
strategies are essential to improve cancer treatment. Metronomic chemotherapy is one such new modality of administering
cytotoxic drugs. Metronomic chemotherapy involves frequent administration of conventional chemotherapeutic agents at
very low doses to target activated endothelial cells in tumors without any drug free break. In addition to reduced acute
toxicity, the efficacy of metronomic chemotherapy seems to increase when administered in combination with specific antiangiogenic
drugs.
Keywords - Anti-angiogenesis, Cancer, Chemotherapy, Metronomic.
Type : Research paper
Published : Volume-5, Issue-4, Spl. Iss-2
DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-10537
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Published on 2018-02-12 |
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