Serum C-Reactive Protein Level and Lipid Profile in Periodontitis and Coronary Artery Disease in People of Mewar Region: A Co-Relation
INTRODUCTION-Many epidemiological studies have investigated the relationship between periodontal disease and
coronary artery disease but their result are heterogenous. This review article is designed to update the association between
periodontal disease and cardiovascular events.
AIM AND OBJECT-To assess whether there is a link between periodontal and coronary artery disease (CAD).
MATERIAL AND METHOD-This study includes 90 subjects, which were divided into 3 groups:
30 subjects -healthy individuals, 30 subjects – having periodontitis, 30 subjects – suffering from CAD
RESULT-The mean OHI-S scores for group 1, 2 and 3 were 0.95 ±0.60, 2.91±0.90, 1.54±0.74 respectively. CRP level
group 2&3 were significantly higher then group 1 ( p=0.002 and 0.00 respectively) where as difference between group 2 & 3
was not significantly significant. Lipid profiles, cholesterol, low density lipoprotein (LDL), triglycerides higher in group 2 as
compare to 1&3. High density lipoprotein (HDL) levels between groups were not significantly different.
CONCLUSION – Based on results and other reports periodontitis may be a risk factor for CAD and possibly there can be
an association between periodontal diseases.
Index terms - C-reactive protein, Coronary artery disease, Lipid metabolism, Periodontitis.