Paper Title
Pharmaceutical Importance of Withania Coagulans in Health and Diseases

Many plants have been reported to cure various health problems and diseases from ancient times. Medicinal plants play a vital role for the development of new drug. Considering all the medicinal properties, the species of genus ‘Withania’ of Solanaceae family are also of great medicinal value. Withania coagulans, commonly known as Indian cheese maker, paneer dodi or panner doda, vegetable rennet. The berries of the shrub are used for milk coagulation. They are also used in dyspepsia, flatulent colic and other intestinal infections. Withania coagulans (Stocks) Dunal is used to treat nervous exhaustion, disability, insomnia, wasting diseases, failure to thrive in children, impotence. Its fruits are used for liver complaints, asthma and biliousness. In particular withanolide isolated from the plants are considered to have Antimicrobial, antiinflammatory, antiumor, hepatoprotective, antihyperglycemic, cardiovascular, immunosuppressive, free radical scavenging, antimutagenic and central nervous system depressant activities of the plant have been reported. This review gives a aerial view mainly on the biological activities of some of the Withania coagulans compounds isolated and a comprehensive view of its pharmaceutical importance’s in the mentioned diseases. Keywords - Solanaceae, Withania coagulans, phytochemistry, Withanolides, antihyperglycemic.