Paper Title
The Application Of Models To The Micrornas Mediated Viral Oncogenesis

Micro RNAs are a recently discovered class of small non coding functional RNAs. These molecules mediate posttranscriptional regulation of gene expression in a sequence specific manner. Micro RNAs are now known to be key players in a variety of biological processes and have been shown to be deregulated in a number of cancers. The discovery of viral encoded micro RNAs, especially from a family of oncogenic viruses, has attracted immense attention towards the possibility of micro RNAs as critical modulators of viral oncogenesis. The host-virus crosstalk mediated by micro RNAs, messenger RNAs and proteins, is complex and involves the different cellular regulatory layers. In this commentary, we describe models of microRNA mediated viral oncogenesis