Determination Of Iron Toxicity On DNA Methylation In zea Mays
Heavy metals are toxic elements that are known to induce multiple diseases in living organisms even at lower
levels of exposure. We investigated the action of Fe2+on DNA methylation using CRED-RA (Coupled Restriction Enzyme
Digestion-Random Amplification) in Zea mays seedlings. The results indicated that all dosesof FeSO4 (50, 100, 200 and 300
mg/l) caused an increase in DNA methylation value and DNA hypermethylation occurred according to the concentrations of
FeSO4. The results of this experiment have clearly shown that iron has epigenetic effect on Zea mays seedlings.
Keywords- FeSO4, Epigenetic, Zea mays, CRED-RA