Synthesis Spectral & Microbial Studies Of Some Methyl-4-Thiazolodinone Derivatives
Derivatives of Methyl -4- Thiazolodinone were synthesized by acid catalyzed condensation of
Schiff base and Thiolactic acid . Five member heterocyclic ring posses multiple biologic activity .Derivative of
Methyl -4- Thiazolodinone have attracted considerable attentions they are involved with pharmacological
activities such as antihypertensive antitumor anti HIV activities . Derivative of Methyl -4- Thiazolodinone
were characterized by FTIR –HNMR element analysis all synthesized compound have been screened for their
antimicrobial activities by using Broth dilution method
Keywords :Schiff base ,five member heterocyclic ring,Tholactic ,IR, NMR.