Paper Title
In-vitro Antidiabetic Potential of Endangered Curcuma Caesia Rhizome Extracts and its Characterization by FTIR and GC/HR-MS Analysis

Curcuma caesia belongs to Zingiberaceae family, Genus Curcuma are highly valued worldwide for their medicinal and economic significance, specifically the use of Curcuma longa (Turmeric) in medication, culinary and cosmetics is well known since centuries. However, the pharmacological importance of other endangered and endemic species i.e. Curcuma caesia declared by forest department of Chhattisgarh has not being extensively studied. Therefore, in the present study the primary phytochemical screening of successive extracts of rhizome of C. caesia were performed for detection of alkaloids, flavonoids, phenols, carbohydrates, protein, glycolipids etc. In another study of plant extracts was also used for the in vitro antidiabetic test by spectroscopic analysis based on alpha amylase inhibition assay. In this study result was compared with standard curcumin and camphor and last conclude the ethyl acetate extracts of rhizome C. caesia showed highest antidiabetic potential as compare to other solvents extracts. Further studies, column chromatography of ethyl acetate extracts was performed for fractionation of compounds which is responsible for antidiabetic activity. Fuctional group analysis of most relevant plant extracts was evaluated by FTIR analysis. Structural compound which were present in C. caesia were examined by GC/HR-MS analysis. Keywords - Curcuma caesia, Antidiabetic, Alpha Amylase, FTIR, GC/HR-MS, Curcumin.